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Explaining variability in ciclosporin exposure in adult kidney transplant recipients

PURPOSE: Optimal ciclosporin A (CsA) exposure in kidney transplant recipients is difficult to attain because of variability in CsA pharmacokinetics. A better understanding of the variability in CsA exposure could be a good means of individualizing therapy. Specifically, genetic variability in genes...

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Detalles Bibliográficos
Autores principales:	Press, Rogier R., Ploeger, Bart A., den Hartigh, Jan, van der Straaten, T., van Pelt, Hans, Danhof, Meindert, de Fijter, Hans, Guchelaar, Henk-Jan
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Pharmacogenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868991/ https://www.ncbi.nlm.nih.gov/pubmed/20354687 http://dx.doi.org/10.1007/s00228-010-0810-9

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