Cargando…

Cellular and molecular phenotypes of proliferating stromal cells from human carcinomas

BACKGROUND: Stromal cells are a functionally important component of human carcinomas. The aim of this study was to obtain and characterise primary cultures of stromal cells from human carcinomas and the corresponding surrounding normal tissue. METHODS: Primary stromal cell cultures from tumours of l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kopantzev, E P, Vayshlya, N A, Kopantseva, M R, Egorov, V I, Pikunov, M, Zinovyeva, M V, Vinogradova, T V, Zborovskaya, I B, Sverdlov, E D
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869161/ https://www.ncbi.nlm.nih.gov/pubmed/20407446 http://dx.doi.org/10.1038/sj.bjc.6605652

Ejemplares similares

Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer
por: Galván, J A, et al.
Publicado: (2015)

Direct T cell–tumour interaction triggers T(H)1 phenotype activation through the modification of the mesenchymal stromal cells transcriptional programme
por: Jin, P, et al.
Publicado: (2014)

Overexpressed vs mutated Kras in murine fibroblasts: a molecular phenotyping study
por: Horsch, M, et al.
Publicado: (2009)

Direct cancer–stromal interaction increases fibroblast proliferation and enhances invasive properties of scirrhous-type gastric carcinoma cells
por: Semba, S, et al.
Publicado: (2009)

Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition
por: Krubasik, D, et al.
Publicado: (2006)

Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma
por: Lau, Y S, et al.
Publicado: (2007)

G-CSF and G-CSFR are highly expressed in human gastric and colon cancers and promote carcinoma cell proliferation and migration
por: Morris, K T, et al.
Publicado: (2014)

Promoters with Cancer Cell-Specific Activity for Melanoma Gene Therapy
por: Pleshkan, V.V., et al.
Publicado: (2011)

Mesenchymal stem cells are enriched in head neck squamous cell carcinoma, correlates with tumour size and inhibit T-cell proliferation
por: Liotta, F, et al.
Publicado: (2015)

Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression
por: Canel, M, et al.
Publicado: (2008)

Sox11 expression in astrocytic gliomas: correlation with nestin/c-Met/IDH1-R132H expression phenotypes, p-Stat-3 and survival
por: Korkolopoulou, P, et al.
Publicado: (2013)

Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism?
por: Arnould, L, et al.
Publicado: (2006)

Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells
por: Kaistha, B P, et al.
Publicado: (2014)

H2AX phosphorylation screen of cells from radiosensitive cancer patients reveals a novel DNA double-strand break repair cellular phenotype
por: Vasireddy, R S, et al.
Publicado: (2010)

Role of human tissue kallikrein in gastrointestinal stromal tumour invasion
por: Dominek, P, et al.
Publicado: (2010)

Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study
por: Aparicio, T, et al.
Publicado: (2013)

Bone marrow-derived stromal cells are associated with gastric cancer progression
por: Kasashima, H, et al.
Publicado: (2015)

Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro
por: Prencipe, M, et al.
Publicado: (2009)

ERK5 signalling in prostate cancer promotes an invasive phenotype
por: Ramsay, A K, et al.
Publicado: (2011)

Molecular profiling of cervical cancer progression
por: Hagemann, T, et al.
Publicado: (2007)

Malten, a new synthetic molecule showing in vitro antiproliferative activity against tumour cells and induction of complex DNA structural alterations
por: Amatori, S, et al.
Publicado: (2010)

Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumours
por: Salto-Tellez, M, et al.
Publicado: (2007)

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
por: Gray-Schopfer, V C, et al.
Publicado: (2006)

Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas
por: Haldorsen, I S, et al.
Publicado: (2014)

Tumour biomarker expression relative to age and molecular subtypes of invasive breast cancer
por: Morrison, D H, et al.
Publicado: (2012)

Impact of cellular folate status and epidermal growth factor receptor expression on BCRP/ABCG2-mediated resistance to gefitinib and erlotinib
por: Lemos, C, et al.
Publicado: (2009)

Asporin is a stromally expressed marker associated with prostate cancer progression
por: Rochette, Annie, et al.
Publicado: (2017)

MiR-17-92 and miR-221/222 cluster members target KIT and ETV1 in human gastrointestinal stromal tumours
por: Gits, C M M, et al.
Publicado: (2013)

Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer
por: Flores, L M, et al.
Publicado: (2010)

The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue
por: Oladipo, O, et al.
Publicado: (2011)

Inflammation and tissue repair markers distinguish the nodular sclerosis and mixed cellularity subtypes of classical Hodgkin's lymphoma
por: Birgersdotter, A, et al.
Publicado: (2009)

Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype
por: Ameri, K, et al.
Publicado: (2010)

Circulating cell-free miRNAs as biomarker for triple-negative breast cancer
por: Shin, V Y, et al.
Publicado: (2015)

CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells
por: Maciaczyk, D, et al.
Publicado: (2017)

Somatostatin receptors 2 and 5 are preferentially expressed in proliferating endothelium
por: Adams, R L, et al.
Publicado: (2005)

The in situ local immune response, tumour senescence and proliferation in colorectal cancer
por: Roxburgh, C S, et al.
Publicado: (2013)

Identification of key clinical phenotypes of breast cancer using a reduced panel of protein biomarkers
por: Green, A R, et al.
Publicado: (2013)

Breast cancer metastasis suppressor-1 promoter methylation in cell-free DNA provides prognostic information in non-small cell lung cancer
por: Balgkouranidou, I, et al.
Publicado: (2014)

BRAF(V600E) melanoma cells secrete factors that activate stromal fibroblasts and enhance tumourigenicity
por: Whipple, C A, et al.
Publicado: (2014)

Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors
por: Bijnsdorp, I V, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_m3m6spfmdn3tam3igoa7p50ptu