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Issues on fit-for-purpose validation of a panel of ELISAs for application as biomarkers in clinical trials of anti-Angiogenic drugs

BACKGROUND: Successful introduction of new anticancer agents into the clinic is often hampered by a lack of qualified biomarkers. Studies have been conducted of 17 ELISAs representing a potential panel of pharmacodynamic/predictive biomarkers for drugs targeted to tumour vasculature. METHODS: The fi...

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Detalles Bibliográficos
Autores principales:	Brookes, K, Cummings, J, Backen, A, Greystoke, A, Ward, T, Jayson, G C, Dive, C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869162/ https://www.ncbi.nlm.nih.gov/pubmed/20407440 http://dx.doi.org/10.1038/sj.bjc.6605661

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