Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer

BACKGROUND: Circulating tumour cells (CTCs) offer a non-invasive approach to obtain and characterise metastatic tumour cells, but their usefulness has been limited by low CTC yields from conventional isolation methods. METHODS: To improve CTC yields and facilitate their molecular characterisation we...

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Detalles Bibliográficos
Autores principales: Flores, L M, Kindelberger, D W, Ligon, A H, Capelletti, M, Fiorentino, M, Loda, M, Cibas, E S, Jänne, P A, Krop, I E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869174/
https://www.ncbi.nlm.nih.gov/pubmed/20461092
http://dx.doi.org/10.1038/sj.bjc.6605676

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