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Age- and Temperature-Dependent Somatic Mutation Accumulation in Drosophila melanogaster
Using a transgenic mouse model harboring a mutation reporter gene that can be efficiently recovered from genomic DNA, we previously demonstrated that mutations accumulate in aging mice in a tissue-specific manner. Applying a recently developed, similar reporter-based assay in Drosophila melanogaster...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869313/ https://www.ncbi.nlm.nih.gov/pubmed/20485564 http://dx.doi.org/10.1371/journal.pgen.1000950 |