Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

Despite recent advances in our understanding of the pathogenesis of attaching and effacing (A/E) Escherichia coli infections, the mechanisms by which the host defends against these microbes are unclear. The goal of this study was to determine the role of goblet cell-derived Muc2, the major intestina...

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Detalles Bibliográficos
Autores principales: Bergstrom, Kirk S. B., Kissoon-Singh, Vanessa, Gibson, Deanna L., Ma, Caixia, Montero, Marinieve, Sham, Ho Pan, Ryz, Natasha, Huang, Tina, Velcich, Anna, Finlay, B. Brett, Chadee, Kris, Vallance, Bruce A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869315/
https://www.ncbi.nlm.nih.gov/pubmed/20485566
http://dx.doi.org/10.1371/journal.ppat.1000902

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