A Domesticated piggyBac Transposase Plays Key Roles in Heterochromatin Dynamics and DNA Cleavage during Programmed DNA Deletion in Tetrahymena thermophila

Transposons comprise large fractions of eukaryotic genomes and provide genetic reservoirs for the evolution of new cellular functions. We identified TPB2, a homolog of the piggyBac transposase gene that is required for programmed DNA deletion in Tetrahymena. TPB2 was expressed exclusively during the...

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Detalles Bibliográficos
Autores principales: Cheng, Chao-Yin, Vogt, Alexander, Mochizuki, Kazufumi, Yao, Meng-Chao
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869380/
https://www.ncbi.nlm.nih.gov/pubmed/20357003
http://dx.doi.org/10.1091/mbc.E09-12-1079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869380/
https://www.ncbi.nlm.nih.gov/pubmed/20357003
http://dx.doi.org/10.1091/mbc.E09-12-1079

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