LIGHT Induces Distinct Signals to Clear an AAV-Expressed Persistent Antigen in the Mouse Liver and to Induce Liver Inflammation

BACKGROUND: Infection with adeno-associated virus (AAV) vector with liver tropism leads to persistent expression of foreign antigens in the mouse liver, with no significant liver inflammation or pathology. This provides a model to investigate antigen persistence in the liver and strategies to modula...

Descripción completa

Detalles Bibliográficos
Autores principales: Washburn, Michael L., Kovalev, Grigoriy I., Koroleva, Ekaterina, Fu, Yang-Xin, Su, Lishan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871052/
https://www.ncbi.nlm.nih.gov/pubmed/20498840
http://dx.doi.org/10.1371/journal.pone.0010585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871052/
https://www.ncbi.nlm.nih.gov/pubmed/20498840
http://dx.doi.org/10.1371/journal.pone.0010585

Ejemplares similares