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Identification of MicroRNA-21 as a Biomarker for Chemoresistance and Clinical Outcome Following Adjuvant Therapy in Resectable Pancreatic Cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. The high risk of recurrence following surgical resection provides the rationale for adjuvant therapy. However, only a subset of patients benefit from adjuvant therapy. Identification of molecular markers to predict treatment...

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Detalles Bibliográficos
Autores principales: Hwang, Jin-Hyeok, Voortman, Johannes, Giovannetti, Elisa, Steinberg, Seth M., Leon, Leticia G., Kim, Yong-Tae, Funel, Niccola, Park, Joo Kyung, Kim, Min A., Kang, Gyeong Hoon, Kim, Sun-Whe, Chiaro, Marco Del, Peters, Godefridus J., Giaccone, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871055/
https://www.ncbi.nlm.nih.gov/pubmed/20498843
http://dx.doi.org/10.1371/journal.pone.0010630

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