Cargando…

Intrinsically Disordered Proteins in Bcl-2 Regulated Apoptosis

Intrinsic cell death is mediated by interaction between pro-apoptotic and pro-survival proteins of the B-cell lymphoma-2 (Bcl-2) family. Members of this family are either intrinsically disordered or contain intrinsically disordered regions/domains that are critical to their function. Alternate splic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rautureau, Gilles J. P., Day, Catherine L., Hinds, Mark G.
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2010
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871139/ https://www.ncbi.nlm.nih.gov/pubmed/20480043 http://dx.doi.org/10.3390/ijms11041808

Ejemplares similares

Metazoans and Intrinsic Apoptosis: An Evolutionary Analysis of the Bcl-2 Family
por: Suraweera, Chathura D., et al.
Publicado: (2022)

The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonist
por: Rautureau, G J P, et al.
Publicado: (2012)

Detection of Bcl-2 family member Bcl-G in mouse tissues using new monoclonal antibodies
por: Giam, M, et al.
Publicado: (2012)

Regulation of apoptosis by an intrinsically disordered region of Bcl-xL
por: Follis, Ariele Viacava, et al.
Publicado: (2018)

Intrinsically Connected: Therapeutically Targeting the Cathepsin Proteases and the Bcl-2 Family of Protein Substrates as Co-regulators of Apoptosis
por: Soond, Surinder M., et al.
Publicado: (2021)

Targeting BCL-2 regulated apoptosis in cancer
por: Campbell, Kirsteen J., et al.
Publicado: (2018)

Structural biology of the Bcl-2 family and its mimicry by viral proteins
por: Kvansakul, M, et al.
Publicado: (2013)

The Bcl-2 Family in Host-Virus Interactions
por: Kvansakul, Marc, et al.
Publicado: (2017)

Zeaxanthin Induces Apoptosis in Human Uveal Melanoma Cells through Bcl-2 Family Proteins and Intrinsic Apoptosis Pathway
por: Bi, Ming-Chao, et al.
Publicado: (2013)

Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus
por: Suraweera, Chathura D., et al.
Publicado: (2022)

The Role of BCL2 Family of Apoptosis Regulator Proteins in Acute and Chronic Leukemias
por: Tzifi, Flora, et al.
Publicado: (2012)

The structural basis of Bcl-2 mediated cell death regulation in hydra
por: Banjara, Suresh, et al.
Publicado: (2020)

The Bcl-2 Family: Ancient Origins, Conserved Structures, and Divergent Mechanisms
por: Banjara, Suresh, et al.
Publicado: (2020)

High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria
por: Esposito, F, et al.
Publicado: (2012)

Regulation of Apoptosis by the Bcl-2 Family of Proteins: Field on a Brink
por: Ladokhin, Alexey S.
Publicado: (2020)

The role of BCL-2 family proteins in regulating apoptosis and cancer therapy
por: Qian, Shanna, et al.
Publicado: (2022)

Bcl-B: an “unknown” protein of the Bcl-2 family
por: Pervushin, N. V., et al.
Publicado: (2023)

Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis
por: Popgeorgiev, Nikolay, et al.
Publicado: (2020)

Biological properties of the BCL-2 family protein BCL-RAMBO, which regulates apoptosis, mitochondrial fragmentation, and mitophagy
por: Kataoka, Takao
Publicado: (2022)

Retraction to: High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria
por: Esposito, F, et al.
Publicado: (2014)

What’s in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered
por: Dunker, A. Keith, et al.
Publicado: (2013)

Intrinsic Order and Disorder in the Bcl-2 Member Harakiri: Insights into Its Proapoptotic Activity
por: Barrera-Vilarmau, Susana, et al.
Publicado: (2011)

Intrinsically Disordered Proteins: An Overview
por: Trivedi, Rakesh, et al.
Publicado: (2022)

RTKN2 Induces NF-KappaB Dependent Resistance to Intrinsic Apoptosis in HEK Cells and Regulates BCL-2 Genes in Human CD4(+) Lymphocytes
por: Collier, Fiona M, et al.
Publicado: (2009)

BCL-2 family isoforms in apoptosis and cancer
por: Warren, Chloe F. A., et al.
Publicado: (2019)

The prognostic significance of apoptosis-associated proteins BCL-2, BAX and BCL-X in clinical nephroblastoma
por: Ghanem, M A, et al.
Publicado: (2001)

The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins
por: Marzo, Isabel, et al.
Publicado: (1998)

Viral Bcl2s’ transmembrane domain interact with host Bcl2 proteins to control cellular apoptosis
por: García-Murria, Maria Jesús, et al.
Publicado: (2020)

Intrinsic Disorder in Proteins with Pathogenic Repeat Expansions
por: Darling, April L., et al.
Publicado: (2017)

Differential regulation of nuclear and mitochondrial Bcl-2 in T cell apoptosis
por: Scheel-Toellner, Dagmar, et al.
Publicado: (2007)

Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity
por: Wilson-Annan, Julie, et al.
Publicado: (2003)

The BCL-2 arbiters of apoptosis and their growing role as cancer targets
por: Adams, Jerry M, et al.
Publicado: (2018)

Targeting intrinsically disordered proteins involved in cancer
por: Santofimia-Castaño, Patricia, et al.
Publicado: (2019)

The alphabet of intrinsic disorder: II. Various roles of glutamic acid in ordered and intrinsically disordered proteins
por: Uversky, Vladimir N
Publicado: (2013)

Expression of Apoptosis‐regulating Proteins Bcl‐2 and Bax in Lymph Node Aspirates from Dogs with Lymphoma
por: Meichner, K., et al.
Publicado: (2016)

Function, Regulation, and Dysfunction of Intrinsically Disordered Proteins
por: Fusco, Giuliana, et al.
Publicado: (2021)

Maspin overexpression modulates tumor cell apoptosis through the regulation of Bcl-2 family proteins
por: Zhang, Weiguo, et al.
Publicado: (2005)

Bcl-2 inhibits apoptosis by increasing the time-to-death and intrinsic cell-to-cell variations in the mitochondrial pathway of cell death
por: Skommer, Joanna, et al.
Publicado: (2010)

Intrinsically Disordered Proteins as Regulators of Transient Biological Processes and as Untapped Drug Targets
por: Hosoya, Yusuke, et al.
Publicado: (2021)

B-Cell Lymphoma 2 (Bcl-2) and Regulation of Apoptosis after Traumatic Brain Injury: A Clinical Perspective
por: Deng, Hansen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ci6m1lo0knk1giprdo7ji4tndm