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Vascularized Fibula Grafts for Reconstruction of Bone Defects after Resection of Bone Sarcomas

We evaluated the results of limb-sparing surgery and reconstruction of bone defects with vascularized fibula grafts in 8 consecutive patients (mean age at operation 13.6 years (range 4.1–24.2 years), female/male = 6/2) with bone sarcomas (BS) (osteosarcoma/Ewing's sarcoma/chondrosarcoma= 4/3/1)...

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Autores principales: Petersen, Michael Mørk, Hovgaard, Dorrit, Elberg, Jens Jørgen, Rechnitzer, Catherine, Daugaard, Søren, Muhic, Aida
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871185/
https://www.ncbi.nlm.nih.gov/pubmed/20490263
http://dx.doi.org/10.1155/2010/524721
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author Petersen, Michael Mørk
Hovgaard, Dorrit
Elberg, Jens Jørgen
Rechnitzer, Catherine
Daugaard, Søren
Muhic, Aida
author_facet Petersen, Michael Mørk
Hovgaard, Dorrit
Elberg, Jens Jørgen
Rechnitzer, Catherine
Daugaard, Søren
Muhic, Aida
author_sort Petersen, Michael Mørk
collection PubMed
description We evaluated the results of limb-sparing surgery and reconstruction of bone defects with vascularized fibula grafts in 8 consecutive patients (mean age at operation 13.6 years (range 4.1–24.2 years), female/male = 6/2) with bone sarcomas (BS) (osteosarcoma/Ewing's sarcoma/chondrosarcoma= 4/3/1) operated on form 2000 to 2006. The bone defects reconstructed were proximal femoral diaphysis and epiphysis (n = 2), humeral diaphysis (n = 2), humeral proximal diaphysis and epiphysis (n = 1), femoral diaphysis (n = 1), ulnar diaphysis (n = 1), and tibial diaphysis (n = 1). One patient with Ewing's sarcoma had an early hip disarticulation, developed multiple metastases, and died 9 months after the operation. The remaining patients (n = 7) are all alive 50 months (range 26–75 months) after surgery. During the follow-up the following major complications were seen: 1-2 fractures (n = 4), pseudarthrosis (n = 2), and hip dislocation (n = 1). Limb-sparing surgery with reconstruction of bone defects using vascularized fibular grafts in BS cases is feasible with acceptable clinical results, but fractures should be expected in many patients.
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spelling pubmed-28711852010-05-20 Vascularized Fibula Grafts for Reconstruction of Bone Defects after Resection of Bone Sarcomas Petersen, Michael Mørk Hovgaard, Dorrit Elberg, Jens Jørgen Rechnitzer, Catherine Daugaard, Søren Muhic, Aida Sarcoma Clinical Study We evaluated the results of limb-sparing surgery and reconstruction of bone defects with vascularized fibula grafts in 8 consecutive patients (mean age at operation 13.6 years (range 4.1–24.2 years), female/male = 6/2) with bone sarcomas (BS) (osteosarcoma/Ewing's sarcoma/chondrosarcoma= 4/3/1) operated on form 2000 to 2006. The bone defects reconstructed were proximal femoral diaphysis and epiphysis (n = 2), humeral diaphysis (n = 2), humeral proximal diaphysis and epiphysis (n = 1), femoral diaphysis (n = 1), ulnar diaphysis (n = 1), and tibial diaphysis (n = 1). One patient with Ewing's sarcoma had an early hip disarticulation, developed multiple metastases, and died 9 months after the operation. The remaining patients (n = 7) are all alive 50 months (range 26–75 months) after surgery. During the follow-up the following major complications were seen: 1-2 fractures (n = 4), pseudarthrosis (n = 2), and hip dislocation (n = 1). Limb-sparing surgery with reconstruction of bone defects using vascularized fibular grafts in BS cases is feasible with acceptable clinical results, but fractures should be expected in many patients. Hindawi Publishing Corporation 2010 2010-05-13 /pmc/articles/PMC2871185/ /pubmed/20490263 http://dx.doi.org/10.1155/2010/524721 Text en Copyright © 2010 Michael Mørk Petersen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Petersen, Michael Mørk
Hovgaard, Dorrit
Elberg, Jens Jørgen
Rechnitzer, Catherine
Daugaard, Søren
Muhic, Aida
Vascularized Fibula Grafts for Reconstruction of Bone Defects after Resection of Bone Sarcomas
title Vascularized Fibula Grafts for Reconstruction of Bone Defects after Resection of Bone Sarcomas
title_full Vascularized Fibula Grafts for Reconstruction of Bone Defects after Resection of Bone Sarcomas
title_fullStr Vascularized Fibula Grafts for Reconstruction of Bone Defects after Resection of Bone Sarcomas
title_full_unstemmed Vascularized Fibula Grafts for Reconstruction of Bone Defects after Resection of Bone Sarcomas
title_short Vascularized Fibula Grafts for Reconstruction of Bone Defects after Resection of Bone Sarcomas
title_sort vascularized fibula grafts for reconstruction of bone defects after resection of bone sarcomas
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871185/
https://www.ncbi.nlm.nih.gov/pubmed/20490263
http://dx.doi.org/10.1155/2010/524721
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