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High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta

BACKGROUND: Imprinted genes show expression from one parental allele only and are important for development and behaviour. This extreme mode of allelic imbalance has been described for approximately 56 human genes. Imprinting status is often disrupted in cancer and dysmorphic syndromes. More subtle...

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Detalles Bibliográficos
Autores principales: Daelemans, Caroline, Ritchie, Matthew E, Smits, Guillaume, Abu-Amero, Sayeda, Sudbery, Ian M, Forrest, Matthew S, Campino, Susana, Clark, Taane G, Stanier, Philip, Kwiatkowski, Dominic, Deloukas, Panos, Dermitzakis, Emmanouil T, Tavaré, Simon, Moore, Gudrun E, Dunham, Ian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871261/
https://www.ncbi.nlm.nih.gov/pubmed/20403199
http://dx.doi.org/10.1186/1471-2156-11-25