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BS Seeker: precise mapping for bisulfite sequencing
BACKGROUND: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not designed for mapping bisulfite-treated reads, where the unmethylated Cs are converted to Ts. We have developed BS Seeker,...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871274/ https://www.ncbi.nlm.nih.gov/pubmed/20416082 http://dx.doi.org/10.1186/1471-2105-11-203 |