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Direct determination of molecular haplotypes by chromosome microdissection
Direct observation of haplotypes is still technical challenging. Here we report a method for the determination of haplotypes through chromosome microdissection. We determine human haplotypes with more than 98.85% accuracy at 24,245 heterozygous single-nucleotide polymorphism (SNP) loci in genome-wid...
Autores principales: | Ma, Li, Xiao, Yan, Huang, Hui, Wang, Qingwei, Rao, Weinian, Feng, Yue, Zhang, Kui, Song, Qing |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871314/ https://www.ncbi.nlm.nih.gov/pubmed/20305652 http://dx.doi.org/10.1038/nmeth.1443 |
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