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Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity
Homologous recombination (HR) provides an efficient mechanism for error-free repair of DNA double-strand breaks (DSBs). However, HR can be also harmful as inappropriate or untimely HR events can give rise to lethal recombination intermediates and chromosome rearrangements. A critical step of HR is t...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871440/ https://www.ncbi.nlm.nih.gov/pubmed/20348101 http://dx.doi.org/10.1074/jbc.M110.110478 |