No better time to FRET: shedding light on host pathogen interactions

Understanding the spatio-temporal subversion of host cell signaling by bacterial virulence factors is key to combating infectious diseases. Following a recent study by Buntru and co-workers published in BMC Biology, we review how fluorescence (Forster) resonance energy transfer (FRET) has been appli...

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Detalles Bibliográficos
Autores principales: Hayward, Richard D, Goguen, Jon D, Leong, John M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871520/
https://www.ncbi.nlm.nih.gov/pubmed/20236488
http://dx.doi.org/10.1186/jbiol225
Descripción
Sumario:Understanding the spatio-temporal subversion of host cell signaling by bacterial virulence factors is key to combating infectious diseases. Following a recent study by Buntru and co-workers published in BMC Biology, we review how fluorescence (Forster) resonance energy transfer (FRET) has been applied to studying host-pathogen interactions and consider the prospects for its future application. See research article http://www.biomedcentral.com/1741-7007/7/81.

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