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Apical polarity in three-dimensional culture systems: where to now?
Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecting these processes but, as discussed in a recent study in BM...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871524/ https://www.ncbi.nlm.nih.gov/pubmed/20092610 http://dx.doi.org/10.1186/jbiol213 |
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author | Inman, Jamie L Bissell, Mina J |
author_facet | Inman, Jamie L Bissell, Mina J |
author_sort | Inman, Jamie L |
collection | PubMed |
description | Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecting these processes but, as discussed in a recent study in BMC Biology on the culture of mammary gland epithelial cells, multiple parameters that influence the model must be taken into account. See research article http://www.biomedcentral.com/1741-7007/7/77. |
format | Text |
id | pubmed-2871524 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-28715242010-07-21 Apical polarity in three-dimensional culture systems: where to now? Inman, Jamie L Bissell, Mina J J Biol Minireview Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecting these processes but, as discussed in a recent study in BMC Biology on the culture of mammary gland epithelial cells, multiple parameters that influence the model must be taken into account. See research article http://www.biomedcentral.com/1741-7007/7/77. BioMed Central 2010 2010-01-21 /pmc/articles/PMC2871524/ /pubmed/20092610 http://dx.doi.org/10.1186/jbiol213 Text en Copyright ©2010 BioMed Central Ltd |
spellingShingle | Minireview Inman, Jamie L Bissell, Mina J Apical polarity in three-dimensional culture systems: where to now? |
title | Apical polarity in three-dimensional culture systems: where to now? |
title_full | Apical polarity in three-dimensional culture systems: where to now? |
title_fullStr | Apical polarity in three-dimensional culture systems: where to now? |
title_full_unstemmed | Apical polarity in three-dimensional culture systems: where to now? |
title_short | Apical polarity in three-dimensional culture systems: where to now? |
title_sort | apical polarity in three-dimensional culture systems: where to now? |
topic | Minireview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871524/ https://www.ncbi.nlm.nih.gov/pubmed/20092610 http://dx.doi.org/10.1186/jbiol213 |
work_keys_str_mv | AT inmanjamiel apicalpolarityinthreedimensionalculturesystemswheretonow AT bissellminaj apicalpolarityinthreedimensionalculturesystemswheretonow |