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Apical polarity in three-dimensional culture systems: where to now?

Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecting these processes but, as discussed in a recent study in BM...

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Detalles Bibliográficos
Autores principales: Inman, Jamie L, Bissell, Mina J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871524/
https://www.ncbi.nlm.nih.gov/pubmed/20092610
http://dx.doi.org/10.1186/jbiol213
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author Inman, Jamie L
Bissell, Mina J
author_facet Inman, Jamie L
Bissell, Mina J
author_sort Inman, Jamie L
collection PubMed
description Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecting these processes but, as discussed in a recent study in BMC Biology on the culture of mammary gland epithelial cells, multiple parameters that influence the model must be taken into account. See research article http://www.biomedcentral.com/1741-7007/7/77.
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spelling pubmed-28715242010-07-21 Apical polarity in three-dimensional culture systems: where to now? Inman, Jamie L Bissell, Mina J J Biol Minireview Delineation of the mechanisms that establish and maintain the polarity of epithelial tissues is essential to understanding morphogenesis, tissue specificity and cancer. Three-dimensional culture assays provide a useful platform for dissecting these processes but, as discussed in a recent study in BMC Biology on the culture of mammary gland epithelial cells, multiple parameters that influence the model must be taken into account. See research article http://www.biomedcentral.com/1741-7007/7/77. BioMed Central 2010 2010-01-21 /pmc/articles/PMC2871524/ /pubmed/20092610 http://dx.doi.org/10.1186/jbiol213 Text en Copyright ©2010 BioMed Central Ltd
spellingShingle Minireview
Inman, Jamie L
Bissell, Mina J
Apical polarity in three-dimensional culture systems: where to now?
title Apical polarity in three-dimensional culture systems: where to now?
title_full Apical polarity in three-dimensional culture systems: where to now?
title_fullStr Apical polarity in three-dimensional culture systems: where to now?
title_full_unstemmed Apical polarity in three-dimensional culture systems: where to now?
title_short Apical polarity in three-dimensional culture systems: where to now?
title_sort apical polarity in three-dimensional culture systems: where to now?
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871524/
https://www.ncbi.nlm.nih.gov/pubmed/20092610
http://dx.doi.org/10.1186/jbiol213
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