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Regulation of metabolism in Caenorhabditis elegans longevity

The nematode Caenorhabditis elegans is a favorite model for the study of aging. A wealth of genetic and genomic studies show that metabolic regulation is a hallmark of life-span modulation. A recent study in BMC Biology identifying metabolic signatures for longevity suggests that amino-acid pools ma...

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Detalles Bibliográficos
Autores principales: Gallo, Marco, Riddle, Donald L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871526/
https://www.ncbi.nlm.nih.gov/pubmed/20156326
http://dx.doi.org/10.1186/jbiol215
Descripción
Sumario:The nematode Caenorhabditis elegans is a favorite model for the study of aging. A wealth of genetic and genomic studies show that metabolic regulation is a hallmark of life-span modulation. A recent study in BMC Biology identifying metabolic signatures for longevity suggests that amino-acid pools may be important in longevity. See research article http://www.biomedcentral.com/1741-7007/8/14.