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Spermatogonial stem cell regulation and spermatogenesis

This article will provide an updated review of spermatogonial stem cells and their role in maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial stem cells (SSCs) will be described, along with research using these tools to enhance our understanding of stem cell biolo...

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Detalles Bibliográficos
Autores principales: Phillips, Bart T., Gassei, Kathrin, Orwig, Kyle E.
Formato: Texto
Lenguaje:English
Publicado: The Royal Society 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871929/
https://www.ncbi.nlm.nih.gov/pubmed/20403877
http://dx.doi.org/10.1098/rstb.2010.0026
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author Phillips, Bart T.
Gassei, Kathrin
Orwig, Kyle E.
author_facet Phillips, Bart T.
Gassei, Kathrin
Orwig, Kyle E.
author_sort Phillips, Bart T.
collection PubMed
description This article will provide an updated review of spermatogonial stem cells and their role in maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial stem cells (SSCs) will be described, along with research using these tools to enhance our understanding of stem cell biology and spermatogenesis. Increased knowledge about the biology of SSCs improves our capacity to manipulate these cells for practical application. The chapter concludes with a discussion of future directions for fundamental investigation and practical applications of SSCs.
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spelling pubmed-28719292010-05-27 Spermatogonial stem cell regulation and spermatogenesis Phillips, Bart T. Gassei, Kathrin Orwig, Kyle E. Philos Trans R Soc Lond B Biol Sci Articles This article will provide an updated review of spermatogonial stem cells and their role in maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial stem cells (SSCs) will be described, along with research using these tools to enhance our understanding of stem cell biology and spermatogenesis. Increased knowledge about the biology of SSCs improves our capacity to manipulate these cells for practical application. The chapter concludes with a discussion of future directions for fundamental investigation and practical applications of SSCs. The Royal Society 2010-05-27 /pmc/articles/PMC2871929/ /pubmed/20403877 http://dx.doi.org/10.1098/rstb.2010.0026 Text en © 2010 The Royal Society http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Phillips, Bart T.
Gassei, Kathrin
Orwig, Kyle E.
Spermatogonial stem cell regulation and spermatogenesis
title Spermatogonial stem cell regulation and spermatogenesis
title_full Spermatogonial stem cell regulation and spermatogenesis
title_fullStr Spermatogonial stem cell regulation and spermatogenesis
title_full_unstemmed Spermatogonial stem cell regulation and spermatogenesis
title_short Spermatogonial stem cell regulation and spermatogenesis
title_sort spermatogonial stem cell regulation and spermatogenesis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871929/
https://www.ncbi.nlm.nih.gov/pubmed/20403877
http://dx.doi.org/10.1098/rstb.2010.0026
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AT gasseikathrin spermatogonialstemcellregulationandspermatogenesis
AT orwigkylee spermatogonialstemcellregulationandspermatogenesis