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Transcript counting in single cells reveals dynamics of rDNA transcription
Most eukaryotes contain many tandem repeats of ribosomal RNA genes of which only a subset is transcribed at any given time. Current biochemical methods allow for the determination of the fraction of transcribing repeats (ON) versus non-transcribing repeats (OFF) but do not provide any dynamical info...
Autores principales: | Tan, Rui Zhen, van Oudenaarden, Alexander |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872610/ https://www.ncbi.nlm.nih.gov/pubmed/20393578 http://dx.doi.org/10.1038/msb.2010.14 |
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