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IL-4Rα-Independent Expression of Mannose Receptor and Ym1 by Macrophages Depends on their IL-10 Responsiveness
IL-4Rα-dependent responses are essential for granuloma formation and host survival during acute schistosomiasis. Previously, we demonstrated that mice deficient for macrophage-specific IL-4Rα (LysM(cre)Il4ra(−/lox)) developed increased hepatotoxicity and gut inflammation; whereas inflammation was re...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872644/ https://www.ncbi.nlm.nih.gov/pubmed/20502521 http://dx.doi.org/10.1371/journal.pntd.0000689 |