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Loss of the Heparan Sulfate Sulfotransferase, Ndst1, in Mammary Epithelial Cells Selectively Blocks Lobuloalveolar Development in Mice

BACKGROUND: Considerable evidence indicates that heparan sulfate is essential for the development of tissues consisting of branching ducts and tubules. However, there are few examples where specific sulfate residues regulate a specific stage in the formation of such tissues. METHODOLOGY/PRINCIPAL FI...

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Detalles Bibliográficos
Autores principales: Crawford, Brett E., Garner, Omai B., Bishop, Joseph R., Zhang, David Y., Bush, Kevin T., Nigam, Sanjay K., Esko, Jeffrey D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872662/
https://www.ncbi.nlm.nih.gov/pubmed/20502530
http://dx.doi.org/10.1371/journal.pone.0010691