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Wnt4 and LAP2alpha as Pacemakers of Thymic Epithelial Senescence

Age-associated thymic involution has considerable physiological impact by inhibiting de novo T-cell selection. This impaired T-cell production leads to weakened immune responses. Yet the molecular mechanisms of thymic stromal adipose involution are not clear. Age-related alterations also occur in th...

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Detalles Bibliográficos
Autores principales:	Kvell, Krisztian, Varecza, Zoltan, Bartis, Domokos, Hesse, Sebastian, Parnell, Sonia, Anderson, Graham, Jenkinson, Eric J., Pongracz, Judit E.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872673/ https://www.ncbi.nlm.nih.gov/pubmed/20502698 http://dx.doi.org/10.1371/journal.pone.0010701

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