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Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil

Potential negative effects of exposure to Nigerian Qua Iboe Brent crude oil on the reproductive system of male rats was investigated. Forty Sprague-Dawley rats were used for the experiment. Exposure to Nigerian Qua Iboe Brent crude oil was achieved via oral administration of increasing doses (0.1, 0...

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Autores principales: Obidike, I. Reginald, Maduabuchi, Igwebuike U., Olumuyiwa, Shoyinka S.V.
Formato: Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872690/
https://www.ncbi.nlm.nih.gov/pubmed/17322767
http://dx.doi.org/10.4142/jvs.2007.8.1.1
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author Obidike, I. Reginald
Maduabuchi, Igwebuike U.
Olumuyiwa, Shoyinka S.V.
author_facet Obidike, I. Reginald
Maduabuchi, Igwebuike U.
Olumuyiwa, Shoyinka S.V.
author_sort Obidike, I. Reginald
collection PubMed
description Potential negative effects of exposure to Nigerian Qua Iboe Brent crude oil on the reproductive system of male rats was investigated. Forty Sprague-Dawley rats were used for the experiment. Exposure to Nigerian Qua Iboe Brent crude oil was achieved via oral administration of increasing doses (0.1, 0.2, and 0.4 ml/rat) every other day for 4 weeks. Cauda epididymal sperm reserves and relative weights of the testes as well as histological features of the testes of rats that received the crude oil treatment were compared to those of control rats. The results described here showed a significant (p < 0.01) dose-dependent reduction in the cauda epididymal sperm reserves of rats that received crude oil treatment relative to the control group. The morphology of testes of the crude oil-exposed rats was characterized by the presence of interstitial exudates, degeneration, and necrosis of spermatogenic and interstitial (Leydig) cells. Findings indicate that exposure of male rats to Nigerian Qua Iboe Brent crude oil may have adversely affected their reproductive systems. This may imply possible reproductive health hazards for animals and humans that may be exposed to this environmental pollutant, especially in areas where oil spillage is a common feature.
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spelling pubmed-28726902010-05-19 Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil Obidike, I. Reginald Maduabuchi, Igwebuike U. Olumuyiwa, Shoyinka S.V. J Vet Sci Original Article Potential negative effects of exposure to Nigerian Qua Iboe Brent crude oil on the reproductive system of male rats was investigated. Forty Sprague-Dawley rats were used for the experiment. Exposure to Nigerian Qua Iboe Brent crude oil was achieved via oral administration of increasing doses (0.1, 0.2, and 0.4 ml/rat) every other day for 4 weeks. Cauda epididymal sperm reserves and relative weights of the testes as well as histological features of the testes of rats that received the crude oil treatment were compared to those of control rats. The results described here showed a significant (p < 0.01) dose-dependent reduction in the cauda epididymal sperm reserves of rats that received crude oil treatment relative to the control group. The morphology of testes of the crude oil-exposed rats was characterized by the presence of interstitial exudates, degeneration, and necrosis of spermatogenic and interstitial (Leydig) cells. Findings indicate that exposure of male rats to Nigerian Qua Iboe Brent crude oil may have adversely affected their reproductive systems. This may imply possible reproductive health hazards for animals and humans that may be exposed to this environmental pollutant, especially in areas where oil spillage is a common feature. The Korean Society of Veterinary Science 2007-03 2007-03-31 /pmc/articles/PMC2872690/ /pubmed/17322767 http://dx.doi.org/10.4142/jvs.2007.8.1.1 Text en Copyright © 2007 The Korean Society of Veterinary Science https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Obidike, I. Reginald
Maduabuchi, Igwebuike U.
Olumuyiwa, Shoyinka S.V.
Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil
title Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil
title_full Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil
title_fullStr Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil
title_full_unstemmed Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil
title_short Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil
title_sort testicular morphology and cauda epididymal sperm reserves of male rats exposed to nigerian qua iboe brent crude oil
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872690/
https://www.ncbi.nlm.nih.gov/pubmed/17322767
http://dx.doi.org/10.4142/jvs.2007.8.1.1
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