Gene ontology analysis for RNA-seq: accounting for selection bias

We present GOseq, an application for performing Gene Ontology (GO) analysis on RNA-seq data. GO analysis is widely used to reduce complexity and highlight biological processes in genome-wide expression studies, but standard methods give biased results on RNA-seq data due to over-detection of differe...

Descripción completa

Detalles Bibliográficos
Autores principales: Young, Matthew D, Wakefield, Matthew J, Smyth, Gordon K, Oshlack, Alicia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872874/
https://www.ncbi.nlm.nih.gov/pubmed/20132535
http://dx.doi.org/10.1186/gb-2010-11-2-r14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872874/
https://www.ncbi.nlm.nih.gov/pubmed/20132535
http://dx.doi.org/10.1186/gb-2010-11-2-r14

Ejemplares similares