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Gene ontology analysis for RNA-seq: accounting for selection bias
We present GOseq, an application for performing Gene Ontology (GO) analysis on RNA-seq data. GO analysis is widely used to reduce complexity and highlight biological processes in genome-wide expression studies, but standard methods give biased results on RNA-seq data due to over-detection of differe...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872874/ https://www.ncbi.nlm.nih.gov/pubmed/20132535 http://dx.doi.org/10.1186/gb-2010-11-2-r14 |