Genomic features defining exonic variants that modulate splicing

BACKGROUND: Single point mutations at both synonymous and non-synonymous positions within exons can have severe effects on gene function through disruption of splicing. Predicting these mutations in silico purely from the genomic sequence is difficult due to an incomplete understanding of the multip...

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Bibliografiska uppgifter
Huvudupphovsmän: Woolfe, Adam, Mullikin, James C, Elnitski, Laura
Materialtyp: Text
Språk:English
Publicerad: BioMed Central 2010
Ämnen:
Research
Länkar:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872880/
https://www.ncbi.nlm.nih.gov/pubmed/20158892
http://dx.doi.org/10.1186/gb-2010-11-2-r20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872880/
https://www.ncbi.nlm.nih.gov/pubmed/20158892
http://dx.doi.org/10.1186/gb-2010-11-2-r20

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