ChIA-PET tool for comprehensive chromatin interaction analysis with paired-end tag sequencing

Chromatin interaction analysis with paired-end tag sequencing (ChIA-PET) is a new technology to study genome-wide long-range chromatin interactions bound by protein factors. Here we present ChIA-PET Tool, a software package for automatic processing of ChIA-PET sequence data, including linker filteri...

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Detalles Bibliográficos
Autores principales: Li, Guoliang, Fullwood, Melissa J, Xu, Han, Mulawadi, Fabianus Hendriyan, Velkov, Stoyan, Vega, Vinsensius, Ariyaratne, Pramila Nuwantha, Mohamed, Yusoff Bin, Ooi, Hong-Sain, Tennakoon, Chandana, Wei, Chia-Lin, Ruan, Yijun, Sung, Wing-Kin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872882/
https://www.ncbi.nlm.nih.gov/pubmed/20181287
http://dx.doi.org/10.1186/gb-2010-11-2-r22
Descripción
Sumario:Chromatin interaction analysis with paired-end tag sequencing (ChIA-PET) is a new technology to study genome-wide long-range chromatin interactions bound by protein factors. Here we present ChIA-PET Tool, a software package for automatic processing of ChIA-PET sequence data, including linker filtering, mapping tags to reference genomes, identifying protein binding sites and chromatin interactions, and displaying the results on a graphical genome browser. ChIA-PET Tool is fast, accurate, comprehensive, user-friendly, and open source (available at http://chiapet.gis.a-star.edu.sg).

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