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Botulinum hemagglutinin disrupts the intercellular epithelial barrier by directly binding E-cadherin
Botulinum neurotoxin is produced by Clostridium botulinum and forms large protein complexes through associations with nontoxic components. We recently found that hemagglutinin (HA), one of the nontoxic components, disrupts the intercellular epithelial barrier; however, the mechanism underlying this...
Autores principales: | Sugawara, Yo, Matsumura, Takuhiro, Takegahara, Yuki, Jin, Yingji, Tsukasaki, Yoshikazu, Takeichi, Masatoshi, Fujinaga, Yukako |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872904/ https://www.ncbi.nlm.nih.gov/pubmed/20457762 http://dx.doi.org/10.1083/jcb.200910119 |
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