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Botulinum hemagglutinin disrupts the intercellular epithelial barrier by directly binding E-cadherin

Botulinum neurotoxin is produced by Clostridium botulinum and forms large protein complexes through associations with nontoxic components. We recently found that hemagglutinin (HA), one of the nontoxic components, disrupts the intercellular epithelial barrier; however, the mechanism underlying this...

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Detalles Bibliográficos
Autores principales: Sugawara, Yo, Matsumura, Takuhiro, Takegahara, Yuki, Jin, Yingji, Tsukasaki, Yoshikazu, Takeichi, Masatoshi, Fujinaga, Yukako
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872904/
https://www.ncbi.nlm.nih.gov/pubmed/20457762
http://dx.doi.org/10.1083/jcb.200910119

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