Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair

A recent study suggested that human Cdc14B phosphatase has a central function in the G2 DNA damage checkpoint. In this study, we show that chicken DT40, human HCT116, and human telomerase reverse transcription–immortalized retinal pigment epithelial cells deleted for the Cdc14A or Cdc14B gene are DN...

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Detalles Bibliográficos
Autores principales: Mocciaro, Annamaria, Berdougo, Eli, Zeng, Kang, Black, Elizabeth, Vagnarelli, Paola, Earnshaw, William, Gillespie, David, Jallepalli, Prasad, Schiebel, Elmar
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872905/
https://www.ncbi.nlm.nih.gov/pubmed/20479464
http://dx.doi.org/10.1083/jcb.200910057

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