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Traumeel S(® )for pain relief following hallux valgus surgery: a randomized controlled trial

BACKGROUND: In spite of recent advances in post-operative pain relief, pain following orthopedic surgery remains an ongoing challenge for clinicians. We examined whether a well known and frequently prescribed homeopathic preparation could mitigate post-operative pain. METHOD: We performed a randomiz...

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Autores principales: Singer, Shepherd R, Amit-Kohn, Michal, Weiss, Samuel, Rosenblum, Jonathan, Maoz, Guy, Samuels, Noah, Lukasiewicz, Esther, Freedman, Laurence, Paltiel, Ora, Itzchaki, Menachem, Niska, Meir, Oberbaum, Menachem
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873239/
https://www.ncbi.nlm.nih.gov/pubmed/20380750
http://dx.doi.org/10.1186/1472-6904-10-9
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author Singer, Shepherd R
Amit-Kohn, Michal
Weiss, Samuel
Rosenblum, Jonathan
Maoz, Guy
Samuels, Noah
Lukasiewicz, Esther
Freedman, Laurence
Paltiel, Ora
Itzchaki, Menachem
Niska, Meir
Oberbaum, Menachem
author_facet Singer, Shepherd R
Amit-Kohn, Michal
Weiss, Samuel
Rosenblum, Jonathan
Maoz, Guy
Samuels, Noah
Lukasiewicz, Esther
Freedman, Laurence
Paltiel, Ora
Itzchaki, Menachem
Niska, Meir
Oberbaum, Menachem
author_sort Singer, Shepherd R
collection PubMed
description BACKGROUND: In spite of recent advances in post-operative pain relief, pain following orthopedic surgery remains an ongoing challenge for clinicians. We examined whether a well known and frequently prescribed homeopathic preparation could mitigate post-operative pain. METHOD: We performed a randomized, double blind, placebo-controlled trial to evaluate the efficacy of the homeopathic preparation Traumeel S(® )in minimizing post-operative pain and analgesic consumption following surgical correction of hallux valgus. Eighty consecutive patients were randomized to receive either Traumeel tablets or an indistinguishable placebo, and took primary and rescue oral analgesics as needed. Maximum numerical pain scores at rest and consumption of oral analgesics were recorded on day of surgery and for 13 days following surgery. RESULTS: Traumeel was not found superior to placebo in minimizing pain or analgesic consumption over the 14 days of the trial, however a transient reduction in the daily maximum post-operative pain score favoring the Traumeel arm was observed on the day of surgery, a finding supported by a treatment-time interaction test (p = 0.04). CONCLUSIONS: Traumeel was not superior to placebo in minimizing pain or analgesic consumption over the 14 days of the trial. A transient reduction in the daily maximum post-operative pain score on the day of surgery is of questionable clinical importance. TRIAL REGISTRATION: This study was registered at ClinicalTrials.gov. # NCT00279513
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spelling pubmed-28732392010-05-20 Traumeel S(® )for pain relief following hallux valgus surgery: a randomized controlled trial Singer, Shepherd R Amit-Kohn, Michal Weiss, Samuel Rosenblum, Jonathan Maoz, Guy Samuels, Noah Lukasiewicz, Esther Freedman, Laurence Paltiel, Ora Itzchaki, Menachem Niska, Meir Oberbaum, Menachem BMC Clin Pharmacol Research article BACKGROUND: In spite of recent advances in post-operative pain relief, pain following orthopedic surgery remains an ongoing challenge for clinicians. We examined whether a well known and frequently prescribed homeopathic preparation could mitigate post-operative pain. METHOD: We performed a randomized, double blind, placebo-controlled trial to evaluate the efficacy of the homeopathic preparation Traumeel S(® )in minimizing post-operative pain and analgesic consumption following surgical correction of hallux valgus. Eighty consecutive patients were randomized to receive either Traumeel tablets or an indistinguishable placebo, and took primary and rescue oral analgesics as needed. Maximum numerical pain scores at rest and consumption of oral analgesics were recorded on day of surgery and for 13 days following surgery. RESULTS: Traumeel was not found superior to placebo in minimizing pain or analgesic consumption over the 14 days of the trial, however a transient reduction in the daily maximum post-operative pain score favoring the Traumeel arm was observed on the day of surgery, a finding supported by a treatment-time interaction test (p = 0.04). CONCLUSIONS: Traumeel was not superior to placebo in minimizing pain or analgesic consumption over the 14 days of the trial. A transient reduction in the daily maximum post-operative pain score on the day of surgery is of questionable clinical importance. TRIAL REGISTRATION: This study was registered at ClinicalTrials.gov. # NCT00279513 BioMed Central 2010-04-12 /pmc/articles/PMC2873239/ /pubmed/20380750 http://dx.doi.org/10.1186/1472-6904-10-9 Text en Copyright ©2010 Singer et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research article
Singer, Shepherd R
Amit-Kohn, Michal
Weiss, Samuel
Rosenblum, Jonathan
Maoz, Guy
Samuels, Noah
Lukasiewicz, Esther
Freedman, Laurence
Paltiel, Ora
Itzchaki, Menachem
Niska, Meir
Oberbaum, Menachem
Traumeel S(® )for pain relief following hallux valgus surgery: a randomized controlled trial
title Traumeel S(® )for pain relief following hallux valgus surgery: a randomized controlled trial
title_full Traumeel S(® )for pain relief following hallux valgus surgery: a randomized controlled trial
title_fullStr Traumeel S(® )for pain relief following hallux valgus surgery: a randomized controlled trial
title_full_unstemmed Traumeel S(® )for pain relief following hallux valgus surgery: a randomized controlled trial
title_short Traumeel S(® )for pain relief following hallux valgus surgery: a randomized controlled trial
title_sort traumeel s(® )for pain relief following hallux valgus surgery: a randomized controlled trial
topic Research article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873239/
https://www.ncbi.nlm.nih.gov/pubmed/20380750
http://dx.doi.org/10.1186/1472-6904-10-9
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