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Astrocytes derived from trisomic human embryonic stem cells express markers of astrocytic cancer cells and premalignant stem-like progenitors

BACKGROUND: Trisomic variants of human embryonic stem cells (hESCs) arise spontaneously in culture. Although trisomic hESCs share many properties with diploid hESCs, they also exhibit features of cancer stem cells. Since most hESC-based therapies will utilize differentiated derivatives, it is impera...

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Detalles Bibliográficos
Autores principales:	Gopalakrishna-Pillai, Sailesh, Iverson, Linda E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873256/ https://www.ncbi.nlm.nih.gov/pubmed/20423517 http://dx.doi.org/10.1186/1755-8794-3-12

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