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Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype

BACKGROUND: A major feature of chronic obstructive pulmonary disease (COPD) is airway remodelling, which includes an increased airway smooth muscle (ASM) mass. The mechanisms underlying ASM remodelling in COPD are currently unknown. We hypothesized that cigarette smoke (CS) and/or lipopolysaccharide...

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Detalles Bibliográficos
Autores principales:	Pera, Tonio, Gosens, Reinoud, Lesterhuis, Andries H, Sami, Riham, Toorn, Marco van der, Zaagsma, Johan, Meurs, Herman
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873257/ https://www.ncbi.nlm.nih.gov/pubmed/20429916 http://dx.doi.org/10.1186/1465-9921-11-48

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