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Cancer models, genomic instability and somatic cellular Darwinian evolution
The biology of cancer is critically reviewed and evidence adduced that its development can be modelled as a somatic cellular Darwinian evolutionary process. The evidence for involvement of genomic instability (GI) is also reviewed. A variety of quasi-mechanistic models of carcinogenesis are reviewed...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873266/ https://www.ncbi.nlm.nih.gov/pubmed/20406436 http://dx.doi.org/10.1186/1745-6150-5-19 |