Cargando…

Large-scale association analysis of TNF/LTA gene region polymorphisms in type 2 diabetes

BACKGROUND: The TNF/LTA locus has been a long-standing T2D candidate gene. Several studies have examined association of TNF/LTA SNPs with T2D but the majority have been small-scale and produced no convincing evidence of association. The purpose of this study is to examine T2D association of tag SNPs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boraska, Vesna, Rayner, Nigel W, Groves, Christopher J, Frayling, Timothy M, Diakite, Mahamadou, Rockett, Kirk A, Kwiatkowski, Dominic P, Day-Williams, Aaron G, McCarthy, Mark I, Zeggini, Eleftheria
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873325/ https://www.ncbi.nlm.nih.gov/pubmed/20459604 http://dx.doi.org/10.1186/1471-2350-11-69

Ejemplares similares

An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity
por: Asimit, Jennifer, et al.
Publicado: (2012)

Association between LTA, TNF and AGER Polymorphisms and Late Diabetic Complications
por: Lindholm, Eero, et al.
Publicado: (2008)

Combining Information from Common Type 2 Diabetes Risk Polymorphisms Improves Disease Prediction
por: Weedon, Michael N, et al.
Publicado: (2006)

A novel cytofluorometric assay for the detection and quantification of glucose-6-phosphate dehydrogenase deficiency
por: Shah, Shivang S., et al.
Publicado: (2012)

TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression
por: Campino, Susana, et al.
Publicado: (2009)

The effect of next-generation sequencing technology on complex trait research
por: Day-Williams, Aaron G, et al.
Publicado: (2011)

Interrogating Type 2 Diabetes Genome-Wide Association Data Using a Biological Pathway-Based Approach
por: Perry, John R.B., et al.
Publicado: (2009)

A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults
por: Randall, Louise M, et al.
Publicado: (2010)

Extended LTA, TNF, LST1 and HLA Gene Haplotypes and Their Association with Rubella Vaccine-Induced Immunity
por: Ovsyannikova, Inna G., et al.
Publicado: (2010)

A Powerful Approach to Sub-Phenotype Analysis in Population-Based Genetic Association Studies
por: Morris, Andrew P, et al.
Publicado: (2010)

Association analysis of the LTA4H gene polymorphisms and pulmonary tuberculosis in 9115 subjects
por: Curtis, James, et al.
Publicado: (2011)

Polymorphisms of the LTA Gene May Contribute to the Risk of Myocardial Infarction: A Meta-Analysis
por: Li, Na, et al.
Publicado: (2014)

The effect of LTA gene polymorphisms on cancer risk: an updated systematic review and meta- analysis
por: Li, Jingdong, et al.
Publicado: (2020)

Association of LTA and SOD Gene Polymorphisms with Cerebral White Matter Hyperintensities in Migraine Patients
por: Ferroni, Patrizia, et al.
Publicado: (2022)

Valid Consent for Genomic Epidemiology in Developing Countries
por: Chokshi, Dave A, et al.
Publicado: (2007)

Host genetic polymorphisms and serological response against malaria in a selected population in Sri Lanka
por: Dewasurendra, Rajika L., et al.
Publicado: (2018)

LTA, LEP, and TNF-a Gene Polymorphisms are Associated with Susceptibility and Overall Survival of Diffuse Large B-Cell lymphoma in an Arab Population: A Case-Control Study
por: Al-Khatib, Sohaib M, et al.
Publicado: (2020)

Lymphotoxin Alpha (LTA) Polymorphism Is Associated with Prognosis of Non-Hodgkin’s Lymphoma in a Chinese Population
por: Zhang, Yan, et al.
Publicado: (2013)

LPS- and LTA-Induced Expression of IL-6 and TNF-α in Neonatal and Adult Blood: Role of MAPKs and NF-κB
por: Koch, Lutz, et al.
Publicado: (2014)

Gene–physical activity interactions in lower extremity performance: inflammatory genes CRP, TNF-α, and LTA in community-dwelling elders
por: Liu, Chiu-Shong, et al.
Publicado: (2017)

Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes Risk
por: Lango, Hana, et al.
Publicado: (2008)

Genetic polymorphisms associated with anti-malarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka
por: Dewasurendra, Rajika L, et al.
Publicado: (2012)

Influence of Synthesis Method on LTA Time-Dependent Stability
por: Belviso, Claudia, et al.
Publicado: (2018)

The effect of guest cations on proton conduction of LTA zeolite
por: Shi, Huaizhong, et al.
Publicado: (2021)

Study of Water Adsorption on EDTA-Modified LTA Zeolites
por: Volavšek, Janez, et al.
Publicado: (2022)

Textile Functionalization Using LTA and FAU Zeolitic Materials
por: Murrieta-Rico, Fabian N., et al.
Publicado: (2022)

CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
por: Lawrence, Robert, et al.
Publicado: (2010)

Host candidate gene polymorphisms and clearance of drug-resistant Plasmodium falciparum parasites
por: Diakite, Mahamadou, et al.
Publicado: (2011)

Further Evidence Supporting a Role for Gs Signal Transduction in Severe Malaria Pathogenesis
por: Auburn, Sarah, et al.
Publicado: (2010)

Genome-Wide Association Analysis of Imputed Rare Variants: Application to Seven Common Complex Diseases
por: Mägi, Reedik, et al.
Publicado: (2012)

A Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity
por: Fedtke, Iris, et al.
Publicado: (2007)

Will the real disease gene please stand up?
por: Shephard, Neil, et al.
Publicado: (2005)

Response of Neutrophils to Extracellular Haemoglobin and LTA in Human Blood System
por: Lee, Sae-Kyung, et al.
Publicado: (2015)

Staphylococcal LTA antagonizes the B cell-mitogenic potential of LPS
por: Kang, Seok-Seong, et al.
Publicado: (2018)

Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?
por: Southam, L., et al.
Publicado: (2009)

GLIDERS - A web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs
por: Lawrence, Robert, et al.
Publicado: (2009)

Interferon-gamma polymorphisms and risk of iron deficiency and anaemia in Gambian children
por: Abuga, Kelvin M., et al.
Publicado: (2020)

Leukotriene A4 hydrolase (LTA4H rs17525495) gene polymorphisms and paradoxical reactions in extrapulmonary tuberculosis
por: Kumar, Selwyn Selva, et al.
Publicado: (2023)

Trans-ethnic study design approaches for fine-mapping
por: Asimit, Jennifer L, et al.
Publicado: (2016)

Replication of Established Common Genetic Variants for Adult BMI and Childhood Obesity in Greek Adolescents: The TEENAGE Study
por: Ntalla, Ioanna, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_qm86hdvk98fgrtn1tan78gbsio