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CD7 in acute myeloid leukemia: correlation with loss of wild-type CEBPA, consequence of epigenetic regulation

BACKGROUND: CD7 is a negative prognostic marker in myeloid malignancies. In acute myeloid leukemia (AML), an inverse correlation exists between expression of wild-type CEBPA and CD7. Aim of this study was to find out whether C/EBPα is a negative regulator of CD7 and which other regulatory mechanisms...

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Detalles Bibliográficos
Autores principales:	Röhrs, Sonja, Scherr, Michaela, Romani, Julia, Zaborski, Margarete, Drexler, Hans G, Quentmeier, Hilmar
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873354/ https://www.ncbi.nlm.nih.gov/pubmed/20398252 http://dx.doi.org/10.1186/1756-8722-3-15

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