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Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients

Several immunotherapeutic approaches rely on antigen-specific T-cells. Restrictions in the T-cell receptor (TCR) repertoire were reported as indicator of anti-tumor cytotoxic T-lymphocyte (CTL) response in various tumor entities. It is unclear yet whether a TCR restriction in peripheral blood mirror...

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Detalles Bibliográficos
Autores principales:	Ochsenreither, Sebastian, Fusi, Alberto, Wojtke, Susanne, Busse, Antonia, Nüssler, Natascha C, Thiel, Eckhard, Keilholz, Ulrich, Nagorsen, Dirk
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873372/ https://www.ncbi.nlm.nih.gov/pubmed/20385014 http://dx.doi.org/10.1186/1479-5876-8-35

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