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Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits
BACKGROUND: Around half million new cases of cervical cancer arise each year, making the development of an effective therapeutic vaccine against HPV a high priority. As the E6 and E7 oncoproteins are expressed in all HPV-16 tumour cells, vaccines expressing these proteins might clear an already esta...
Autores principales: | Radaelli, Antonia, Pozzi, Eleana, Pacchioni, Sole, Zanotto, Carlo, Morghen, Carlo De Giuli |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873375/ https://www.ncbi.nlm.nih.gov/pubmed/20409340 http://dx.doi.org/10.1186/1479-5876-8-40 |
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