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Increased Rac1 activity and Pak1 overexpression are associated with lymphovascular invasion and lymph node metastasis of upper urinary tract cancer

BACKGROUND: Lymphovascular invasion (LVI) and lymph node metastasis are conventional pathological factors associated with an unfavorable prognosis of urothelial carcinoma of the upper urinary tract (UC-UUT), but little is known about the molecular mechanisms underlying LVI and nodal metastasis in th...

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Detalles Bibliográficos
Autores principales:	Kamai, Takao, Shirataki, Hiromichi, Nakanishi, Kimihiro, Furuya, Nobutaka, Kambara, Tsunehito, Abe, Hideyuki, Oyama, Tetsunari, Yoshida, Ken-Ichiro
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873391/ https://www.ncbi.nlm.nih.gov/pubmed/20426825 http://dx.doi.org/10.1186/1471-2407-10-164

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