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Discovery of High-Affinity Protein Binding Ligands – Backwards

BACKGROUND: There is a pressing need for high-affinity protein binding ligands for all proteins in the human and other proteomes. Numerous groups are working to develop protein binding ligands but most approaches develop ligands using the same strategy in which a large library of structured ligands...

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Detalles Bibliográficos
Autores principales:	Diehnelt, Chris W., Shah, Miti, Gupta, Nidhi, Belcher, Paul E., Greving, Matthew P., Stafford, Phillip, Johnston, Stephen Albert
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873402/ https://www.ncbi.nlm.nih.gov/pubmed/20502719 http://dx.doi.org/10.1371/journal.pone.0010728

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