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Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells

BACKGROUND: The class 1 carcinogen cadmium (Cd(2+)) disrupts the E-cadherin/β-catenin complex of epithelial adherens junctions (AJs) and causes renal cancer. Deregulation of E-cadherin adhesion and changes in Wnt/β-catenin signaling are known to contribute to carcinogenesis. RESULTS: We investigated...

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Detalles Bibliográficos
Autores principales:	Chakraborty, Prabir K, Lee, Wing-Kee, Molitor, Malte, Wolff, Natascha A, Thévenod, Frank
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873433/ https://www.ncbi.nlm.nih.gov/pubmed/20459685 http://dx.doi.org/10.1186/1476-4598-9-102

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