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Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells

BACKGROUND: Castration resistant prostate cancer (CRPC) develops as a consequence of hormone therapies used to deplete androgens in advanced prostate cancer patients. CRPC cells are able to grow in a low androgen environment and this is associated with anomalous activity of their endogenous androgen...

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Detalles Bibliográficos
Autores principales: Chen, Mengqian, Feuerstein, Michael A, Levina, Elina, Baghel, Prateek S, Carkner, Richard D, Tanner, Matthew J, Shtutman, Michael, Vacherot, Francis, Terry, Stéphane, de la Taille, Alexandre, Buttyan, Ralph
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873440/
https://www.ncbi.nlm.nih.gov/pubmed/20420697
http://dx.doi.org/10.1186/1476-4598-9-89