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Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells
BACKGROUND: Castration resistant prostate cancer (CRPC) develops as a consequence of hormone therapies used to deplete androgens in advanced prostate cancer patients. CRPC cells are able to grow in a low androgen environment and this is associated with anomalous activity of their endogenous androgen...
Autores principales: | Chen, Mengqian, Feuerstein, Michael A, Levina, Elina, Baghel, Prateek S, Carkner, Richard D, Tanner, Matthew J, Shtutman, Michael, Vacherot, Francis, Terry, Stéphane, de la Taille, Alexandre, Buttyan, Ralph |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873440/ https://www.ncbi.nlm.nih.gov/pubmed/20420697 http://dx.doi.org/10.1186/1476-4598-9-89 |
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