Cargando…

Arthroscopy vs. MRI for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of MRI in clinical practice

BACKGROUND: In patients with osteoarthritis, a detailed assessment of degenerative cartilage disease is important to recommend adequate treatment. Using a representative sample of patients, this study investigated whether MRI is reliable for a detailed cartilage assessment in patients with osteoarth...

Descripción completa

Detalles Bibliográficos
Autores principales: von Engelhardt, Lars V, Lahner, Matthias, Klussmann, André, Bouillon, Bertil, Dàvid, Andreas, Haage, Patrick, Lichtinger, Thomas K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873463/
https://www.ncbi.nlm.nih.gov/pubmed/20406481
http://dx.doi.org/10.1186/1471-2474-11-75
_version_ 1782181346476556288
author von Engelhardt, Lars V
Lahner, Matthias
Klussmann, André
Bouillon, Bertil
Dàvid, Andreas
Haage, Patrick
Lichtinger, Thomas K
author_facet von Engelhardt, Lars V
Lahner, Matthias
Klussmann, André
Bouillon, Bertil
Dàvid, Andreas
Haage, Patrick
Lichtinger, Thomas K
author_sort von Engelhardt, Lars V
collection PubMed
description BACKGROUND: In patients with osteoarthritis, a detailed assessment of degenerative cartilage disease is important to recommend adequate treatment. Using a representative sample of patients, this study investigated whether MRI is reliable for a detailed cartilage assessment in patients with osteoarthritis of the knee. METHODS: In a cross sectional-study as a part of a retrospective case-control study, 36 patients (mean age 53.1 years) with clinically relevant osteoarthritis received standardized MRI (sag. T1-TSE, cor. STIR-TSE, trans. fat-suppressed PD-TSE, sag. fat-suppressed PD-TSE, Siemens Magnetom Avanto syngo MR B 15) on a 1.5 Tesla unit. Within a maximum of three months later, arthroscopic grading of the articular surfaces was performed. MRI grading by two blinded observers was compared to arthroscopic findings. Diagnostic values as well as intra- and inter-observer values were assessed. RESULTS: Inter-observer agreement between readers 1 and 2 was good (kappa = 0.65) within all compartments. Intra-observer agreement comparing MRI grading to arthroscopic grading showed moderate to good values for readers 1 and 2 (kappa = 0.50 and 0.62, respectively), the poorest being within the patellofemoral joint (kappa = 0.32 and 0.52). Sensitivities were relatively low at all grades, particularly for grade 3 cartilage lesions. A tendency to underestimate cartilage disorders on MR images was not noticed. CONCLUSIONS: According to our results, the use of MRI for precise grading of the cartilage in osteoarthritis is limited. Even if the practical benefit of MRI in pretreatment diagnostics is unequivocal, a diagnostic arthroscopy is of outstanding value when a grading of the cartilage is crucial for a definitive decision regarding therapeutic options in patients with osteoarthritis.
format Text
id pubmed-2873463
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-28734632010-05-20 Arthroscopy vs. MRI for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of MRI in clinical practice von Engelhardt, Lars V Lahner, Matthias Klussmann, André Bouillon, Bertil Dàvid, Andreas Haage, Patrick Lichtinger, Thomas K BMC Musculoskelet Disord Research Article BACKGROUND: In patients with osteoarthritis, a detailed assessment of degenerative cartilage disease is important to recommend adequate treatment. Using a representative sample of patients, this study investigated whether MRI is reliable for a detailed cartilage assessment in patients with osteoarthritis of the knee. METHODS: In a cross sectional-study as a part of a retrospective case-control study, 36 patients (mean age 53.1 years) with clinically relevant osteoarthritis received standardized MRI (sag. T1-TSE, cor. STIR-TSE, trans. fat-suppressed PD-TSE, sag. fat-suppressed PD-TSE, Siemens Magnetom Avanto syngo MR B 15) on a 1.5 Tesla unit. Within a maximum of three months later, arthroscopic grading of the articular surfaces was performed. MRI grading by two blinded observers was compared to arthroscopic findings. Diagnostic values as well as intra- and inter-observer values were assessed. RESULTS: Inter-observer agreement between readers 1 and 2 was good (kappa = 0.65) within all compartments. Intra-observer agreement comparing MRI grading to arthroscopic grading showed moderate to good values for readers 1 and 2 (kappa = 0.50 and 0.62, respectively), the poorest being within the patellofemoral joint (kappa = 0.32 and 0.52). Sensitivities were relatively low at all grades, particularly for grade 3 cartilage lesions. A tendency to underestimate cartilage disorders on MR images was not noticed. CONCLUSIONS: According to our results, the use of MRI for precise grading of the cartilage in osteoarthritis is limited. Even if the practical benefit of MRI in pretreatment diagnostics is unequivocal, a diagnostic arthroscopy is of outstanding value when a grading of the cartilage is crucial for a definitive decision regarding therapeutic options in patients with osteoarthritis. BioMed Central 2010-04-20 /pmc/articles/PMC2873463/ /pubmed/20406481 http://dx.doi.org/10.1186/1471-2474-11-75 Text en Copyright © 2010 von Engelhardt et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
von Engelhardt, Lars V
Lahner, Matthias
Klussmann, André
Bouillon, Bertil
Dàvid, Andreas
Haage, Patrick
Lichtinger, Thomas K
Arthroscopy vs. MRI for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of MRI in clinical practice
title Arthroscopy vs. MRI for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of MRI in clinical practice
title_full Arthroscopy vs. MRI for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of MRI in clinical practice
title_fullStr Arthroscopy vs. MRI for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of MRI in clinical practice
title_full_unstemmed Arthroscopy vs. MRI for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of MRI in clinical practice
title_short Arthroscopy vs. MRI for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of MRI in clinical practice
title_sort arthroscopy vs. mri for a detailed assessment of cartilage disease in osteoarthritis: diagnostic value of mri in clinical practice
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873463/
https://www.ncbi.nlm.nih.gov/pubmed/20406481
http://dx.doi.org/10.1186/1471-2474-11-75
work_keys_str_mv AT vonengelhardtlarsv arthroscopyvsmriforadetailedassessmentofcartilagediseaseinosteoarthritisdiagnosticvalueofmriinclinicalpractice
AT lahnermatthias arthroscopyvsmriforadetailedassessmentofcartilagediseaseinosteoarthritisdiagnosticvalueofmriinclinicalpractice
AT klussmannandre arthroscopyvsmriforadetailedassessmentofcartilagediseaseinosteoarthritisdiagnosticvalueofmriinclinicalpractice
AT bouillonbertil arthroscopyvsmriforadetailedassessmentofcartilagediseaseinosteoarthritisdiagnosticvalueofmriinclinicalpractice
AT davidandreas arthroscopyvsmriforadetailedassessmentofcartilagediseaseinosteoarthritisdiagnosticvalueofmriinclinicalpractice
AT haagepatrick arthroscopyvsmriforadetailedassessmentofcartilagediseaseinosteoarthritisdiagnosticvalueofmriinclinicalpractice
AT lichtingerthomask arthroscopyvsmriforadetailedassessmentofcartilagediseaseinosteoarthritisdiagnosticvalueofmriinclinicalpractice