Extracorporeal immune therapy with immobilized agonistic anti-Fas antibodies leads to transient reduction of circulating neutrophil numbers and limits tissue damage after hemorrhagic shock/resuscitation in a porcine model

BACKGROUND: Hemorrhagic shock/resuscitation is associated with aberrant neutrophil activation and organ failure. This experimental porcine study was done to evaluate the effects of Fas-directed extracorporeal immune therapy with a leukocyte inhibition module (LIM) on hemodynamics, neutrophil tissue...

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Detalles Bibliográficos
Autores principales: Lögters, Tim T, Altrichter, Jens, Paunel-Görgülü, Adnana, Sager, Martin, Witte, Ingo, Ott, Annina, Sadek, Sarah, Baltes, Jessica, Bitu-Moreno, José, Schek, Alberto, Müller, Wolfram, Jeri, Teresa, Windolf, Joachim, Scholz, Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873502/
https://www.ncbi.nlm.nih.gov/pubmed/20406470
http://dx.doi.org/10.1186/1476-9255-7-18

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