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Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study
BACKGROUND: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key mechanism in this technique is to design efficient siRNAs that incorporated into the RNA-induced silencing complexes (RI...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873531/ https://www.ncbi.nlm.nih.gov/pubmed/20380733 http://dx.doi.org/10.1186/1471-2105-11-181 |