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Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
BACKGROUND: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized platform used to detect alternative splicing on a genome-wide scale. Two probe summarization algorithms, PLIER (Probe Logari...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873539/ https://www.ncbi.nlm.nih.gov/pubmed/20426803 http://dx.doi.org/10.1186/1471-2105-11-211 |