Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice

CD8+ T cells are an essential component of an effective host immune response to tumors and viral infections. Genetic immunization is particularly suitable for inducing CTL responses, because the encoded proteins enter the MHC class I processing pathway through either transgene expression or cross-pr...

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Detalles Bibliográficos
Autores principales: Negri, Donatella R. M., Michelini, Zuleika, Baroncelli, Silvia, Spada, Massimo, Vendetti, Silvia, Bona, Roberta, Leone, Pasqualina, Klotman, Mary E., Cara, Andrea
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873659/
https://www.ncbi.nlm.nih.gov/pubmed/20508727
http://dx.doi.org/10.1155/2010/534501

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