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High-throughput analysis of chromosome translocations and other genome rearrangements in epithelial cancers

Genes that are broken or fused by structural changes to the genome are an important class of mutation in the leukemias and sarcomas but have been largely overlooked in the common epithelial cancers. Large-scale sequencing is changing our perceptions of the cancer genome, and it is now being applied...

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Detalles Bibliográficos
Autores principales: Newman, Scott, Edwards, Paul AW
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873797/
https://www.ncbi.nlm.nih.gov/pubmed/20236477
http://dx.doi.org/10.1186/gm140