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Susceptibility to Anthrax Lethal Toxin-Induced Rat Death Is Controlled by a Single Chromosome 10 Locus That Includes rNlrp1

Anthrax lethal toxin (LT) is a bipartite protease-containing toxin and a key virulence determinant of Bacillus anthracis. In mice, LT causes the rapid lysis of macrophages isolated from certain inbred strains, but the correlation between murine macrophage sensitivity and mouse strain susceptibility...

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Detalles Bibliográficos
Autores principales:	Newman, Zachary L., Printz, Morton P., Liu, Shihui, Crown, Devorah, Breen, Laura, Miller-Randolph, Sharmina, Flodman, Pamela, Leppla, Stephen H., Moayeri, Mahtab
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873920/ https://www.ncbi.nlm.nih.gov/pubmed/20502689 http://dx.doi.org/10.1371/journal.ppat.1000906

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